Below you will find a list of player-submitted optimized layouts for solving different portions of the production pipeline in DSP. If you have a layout you'd like to submit, go ahead and add it!
Falk's Guide
Discord/Steam user Falk has created a guide on Steam with several great layouts:
https://steamcommunity.com/sharedfiles/filedetails/?id=2373611284
Mining
The Conveyor Belt Mk.I can carry 6 items per second or 360 items per minute. A Mining Machine that is covering exactly 6 veins will produce 180 items per second. Combining the belts from two mining machines will fully saturate a Conveyor Belt Mk.I with a full 360 items per minute. Note: Mining machines can cover the same resource veins, as shown in the picture below.
Energy Matrix
by Reddit user u/oldshavingfoam
Deuterium
by Reddit user u/oldshavingfoam